It has distinct effects in the treatment of inflammatory disease. Compared to the long history of Chinese medicine, the concept of combination therapy for the treatment of diseases has only recently become popular. From a therapeutic point of view, it seems acceptable that using a combinatorial approach of drugs to hit multiple targets could be a better way to control complex diseases. This could be due to the complexity of the endogenous promoter on target gene expression. For example, Peoria Lactiflora herb 55 is used to treat painful or inflammatory disorders in traditional Chinese medicine.
Paeonia Lactiflora and Lycium barbarum have anti-inflammatory activity 29 , 30 , Acanthopanax senticosus herb 56 is reported to have pharmacological action in the treatment of various diseases, such as chronic renal failure, rheumatics, diabetes mellitus, chronic bronchitis, hypertension, gastric ulcers and ischemic heart diseases 32 , 33 , Other categories of herbs were also studied and actually showed much less frequency of poly-anti-inflammatory properties.
It should be pointed out other categories of herbs could also affect inflammation but have much less frequency in having poly inflammatory properties. The data is unpublished and not shown here. Further studies of other categories of herbs are currently under investigation. The results of the study provided valuable database information that can be mined for the active chemical s components.
Once determined, these ingredients can be further developed into an even more potent anti-inflammation drug. One way to do this is by determining the intersection of different chemical components between different herbs and eliminating it in order to deduce the unique constituent compounds. Though we did not test all anti-inflammation-related pathways and all the TLR-like activities, the proportion of herbs having multiple anti-inflammatory activity could be even higher.
E Journals: Useful Journals for Chinese Medicine and Acupuncture
By studying these herbs, we propose a new paradigm for isolating effective anti-inflammatory compounds that can ultimately lead to new drug discoveries. To subject the extract for E. Chemical fingerprints of all the herbs studied were done using LC-MS technology. The data is stored in the database of our laboratory and is accessible to the public upon request.
Details of COX2 enzyme assay were published in our previous report The prostanoid product was quantified by LC-MS. Details of iNOS enzyme assay were published in our previous report The fold increase or decrease was determined relative to a blank control after normalized.
The normal control group no herb-treated group was used as the baseline. Lun, Y. Anti-inflammatory and immunosuppressive activities of 1,3-dicyclopentyl-1,2,3,6-tetrahydropyrimidine-4,5-dicarboxylic acid diethyl ester ZL Immunopharmacol 17 , — Kroncke, K. Inducible nitric oxide synthase-derived nitric oxide in gene regulation cell death and cell survival.
Int Immunopharmacol 1 , — Surh, Y. Molecular mechanisms underlying chemopreventive activities of anti-inflammatory phytochemicals: down-regulation of COX-2 and iNOS through suppression of NF-kB activation. Guschin, D. Embol J 14 , — Hirano, T. Signaling mechanisms throughgp a model of the cytokine system. Cytokine Growth Factor Rev. Roles of STAT3 in mediating the cell growth, differentiation and survivial signals relayed trough the IL-6 family of cytokine receptors.
Oncogene 19 , — Chalaris, A. The soluble interleukin 6 receptor: generation and role in inflammation and cancer. Eur J Cell Biol.
Taga, T. Interleukin-6 triggers the association of its receptor with a possible signal transgucer, gp Schroder, K. Journal of Leukocyte Biology. Nomura, Y. Life Sci. Han, Z. AP-1 and NK-kB regulation in rheumatoid arthritis and murine collagen-induced arthritis. Autoimmunity 28 , — Schottelius, A.
Interleukin signaling blocks inhibitor of kappaB kinase activity and nuclear factor kappaB DNA binding. J Biol Chem. Chen, C. Selective inhibition of E-selectin, vascular cell adhesion molecule-1, and intercellular adhesion molecule-1 expression by inhibitors of I kappaB-alpha phosphorylation. J Immunol. Barnes, P. How corticosteroids control inflammation: quintiles prize lecture Br J Pharmacol.
Midwest College of Oriental Medicine |
Rhen, T. Antiinflammatory action of glucocorticoids-new mechanisms for old drugs. N Engl J Med. Kaisho, T. Toll-like receptor function and signaling. Allergy Clin.
ITM has distributed hundreds of articles to thousands of practitioners worldwide. The articles range from up-to-date herb safety information to new research about disease treatment, from exploring the main theories behind the treatment methods to the rich history of Chinese medicine and its key contributors. Please spend some time exploring the site to see the variety of content provided.
A Patient’s Guide to Chinese Medicine
A continuation of Anatomy 1, this course is an in-depth study of visceral structure and physiologic function of the human body. This course is an in-depth study of the somatic structure of the human body: skeletal, muscular, ligamentous, and an introduction to the peripheral nerves. There is attention given to the palpatory anatomy that will be needed for Point Location and Needle Technique classes. In this course, students are oriented to the procedures and protocol needed to successfully complete internship. Physical assessment skills needed in the practice of Oriental Medicine are covered including: vital signs, temperature, pulse, and blood pressure.
This course includes discussion that brings up pertinent issues in healthcare practice and examines the approach taken by a counselor. It focuses on ethical decision-making and the patient practitioner relationship. The directed learning paper traces the development of Chinese medicine including: the classics, historical figures and periods, and a discussion of important theoretical developments. It gives students a respect for the ancient traditions from which the modern, clinical practice of TCM developed. The moral and ethical principles that are the core of the teachings of Confucius and Lao Tzu are taught in a manner that can be applied in present day.
The influence of these schools on the development of Chinese medicine is stressed in this course. This course continues massage techniques to regions of the body for local and systemic problem. Good Tui Na technique combined with accessory techniques is an important adjunct to an acupuncture practice. Tui Na is a form of Chinese massage that includes different hand techniques applied to specific areas of the body. Students will gain proficiency in manipulation skill and sensitivity to energy balancing as they practice techniques in class and apply them in clinic.
Students will attend lectures, demonstrate and practice in the traditional and modern accessory techniques of Oriental Medicine: moxibustion, magnets, guasha, cupping and auricular techniques. In this course, students will use charts, models and their fellow students as subjects to locate and mark the most important acupuncture points.
Students will spend six quarters developing the sensitivity needed to achieve the Qi sensation required for effective treatment.
- Hollow Vows.
- The Kissing Bridge (Seven Brides for Seven Bachelors)!
- Article metrics.
- Traditional Chinese Medicine!
- United Earth: The Revelation.
This course further studies the eight principle theory as it applies to the pathology of the five phases, the Zang Fu organs and the triple burner.
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