Direct association of occludin with ZO-1 and its possible involvement in the localization of occludin at tight junctions. Claudin-1 and novel integral membrane proteins localizing at tight junctions with no sequence similarity to occludin. A single gene product, claudin-1 or -2, reconstitutes tight junction strands and recruits occludin in fibroblasts. Manner of interaction of heterogeneous claudin species within and between tight junction strands. Conversion of zonulae occludentes from tight to leaky strand type by introducing claudin-2 into Madin-Darby canine kidney I cells.
Claudin-based tight junctions are crucial for the mammalian epidermal barrier: a lesson from claudindeficient mice. Ghanem, N.
Regulatory roles of conserved intergenic domains in vertebrate Dlx bigene clusters. Gonzalez-Mariscal, L. MAGUK proteins: structure and role in the tight junction. Cell Dev. Tight junction proteins. Gow, A. Cell 99 , Gruenheid, S. Microbial pathogenesis and cytoskeletal function. Nature , Gumbiner, B.
Identification of a kDa polypeptide that binds to the tight junction protein ZO USA 88 , Gye, M. Changes in the expression of claudins and transepithelial electrical resistance of mouse Sertoli cells by Leydig cell coculture. Expression of claudin-1 in mouse testis. Effects of flutamide in the rat testis on the expression of occludin, an integral member of the tight junctions. Hamazaki, Y. Multi-PDZ domain protein 1 MUPP1 is concentrated at tight junctions through its possible interaction with claudin-1 and junctional adhesion molecule.
Hamm, S. Astrocyte mediated modulation of blood-brain barrier permeability does not correlate with a loss of tight junction proteins from the cellular contacts. Cell Tissue. Harris, B. Mechanism and role of PDZ domains in signaling complex assembly. Cell Sci. Haskins, J. Heiskala, M.
The roles of claudin superfamily proteins in paracellular transport. Traffic 2 , 93 Hoevel, T. Cancer , Hofman, P. Noisy-le-grand 49 , 65 Hough, C. Large-scale serial analysis of gene expression reveals genes differentially expressed in ovarian cancer. Hurd, T. Direct interaction of two polarity complexes implicated in epithelial tight junction assembly. Ikenouchi, J. Ishizaki, T. Cyclic AMP induces phosphorylation of claudin-5 immunoprecipitates and expression of claudin-5 gene in blood-brain-barrier endothelial cells via protein kinase A-dependent and -independent pathways.
Current Topics in Membranes
Itoh, M. The kD protein colocalizing with cadherins in non-epithelial cells is identical to ZO-1, a tight junction-associated protein in epithelial cells: cDNA cloning and immunoelectron microscopy. Ito, T. Effect of glucose polymer on the intercellular junctions of cultured human peritoneal mesothelial cells.
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Jesaitis, L. Molecular characterization and tissue distribution of ZO-2, a tight junction protein homologous to ZO-1 and the Drosophila discs-large tumor suppressor protein. Kamimura, Y. Barrier function of microvessels and roles of glial cell line-derived neurotrophic factor in the rat testis. Katoh, M. Kawabe, H. Pilt, a novel peripheral membrane protein at tight junctions in epithelial cells.
Kis, B. Chronic adrenomedullin treatment improves blood-brain barrier function but has no effects on expression of tight junction proteins. Kitajiri, S. Expression patterns of claudins, tight junction adhesion molecules, in the inner ear. Kiuchi-Saishin, Y. Differential expression patterns of claudins, tight junction membrane proteins, in mouse nephron segments. Kojima, T. Role of the p38 MAP-kinase signaling pathway for Cx32 and claudin-1 in the rat liver.
Cell Commun. Kollmar, R. Expression and phylogeny of claudins in vertebrate primordia. USA 98 , Kominsky, S. Loss of the tight junction protein claudin-7 correlates with histological grade in both ductal carcinoma in situ and invasive ductal carcinoma of the breast. Kramer, F. Genomic organization of claudin-1 and its assessment in hereditary and sporadic breast cancer. Kubota, H. Retinoid X receptor alpha and retinoic acid receptor gamma mediate expression of genes encoding tight-junction proteins and barrier function in F9 cells during visceral endodermal differentiation.
Neutrophil transmigration in inflammatory bowel disease is associated with differential expression of epithelial intercellular junction proteins. Kyte, J. A simple method for displaying the hydropathic character of a protein. Lemmers, C. Li, D. Oncogenic Raf-1 disrupts epithelial tight junctions via downregulation of occludin.
Dynamic behavior of paired claudin strands within apposing plasma membranes | PNAS
Li, W. Expression of Claudins 7 and 8 Along the Mouse Nephron. Madara, J. Loosening tight junctions. Lessons from the intestine. Regulation of the movement of solutes across tight junctions. Matsuda, M. A peculiar internalization of claudins, tight junction-specific adhesion molecules, during the intercellular movement of epithelial cells. Mazzon, E. Role of iNOS in hepatocyte tight junction alteration in mouse model of experimental colitis. Noisy-le-grand 49 , 45 Role of IL in hepatocyte tight junction alteration in mouse model of experimental colitis. Michl, P. Claudin a new target for pancreatic cancer treatment using Clostridium perfringens enterotoxin.
Claudin-4 expression decreases invasiveness and metastatic potential of pancreatic cancer. Cancer Res.
Barrier Function of Epithelial Cells
Mitic, L. Molecular architecture of tight junctions. Miwa, N. Morita, K. Claudin multigene family encoding four-transmembrane domain protein components of tight junction strands.
Related Claudins (Current Topics in Membranes)
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